Prime ground-floor commercial space available along the highly trafficked Mission Street corridor. This well-positioned storefront offers excellent visibility, strong pedestrian activity, and convenient access to public transportation. The space features a wide frontage, large display windows, and an efficient open layout suitable for a variety of neighborhood-serving retail or service uses. Located in a dense residential and commercial area, the property benefits from consistent foot traffic and nearby amenities. Ideal for retail, personal services, professional offices, or other permitted commercial uses. Excellent opportunity to establish a presence in one of San Franciscos most active corridors. Highlights: Prominent Mission Street frontage Strong foot and vehicle traffic Ground-floor storefront Flexible open layout Close proximity to BART, MUNI, and bus lines Surrounded by dense residential and commercial uses
MLS #
ML82029485
MLS Source
MLSListings, Inc.
Days on Site
1
Parking Spaces
0
Utilities
Public Utilities, Water - Public
Cooling
Other
Heating
Other
Roof
Other
Foundation
Other
Sewer
Public Sewer
Water
Public
Zoning
NC2
4221 Mission St is a Commercial Lease in San Francisco, CA 94112. This 757 square foot property sits on a 10,084 Sq Ft Lot and features – bedrooms & – full bathrooms. It is currently priced at $1,999 and was built in 1977. This address can also be written as 4221 Mission St, San Francisco, CA 94112.
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This listing information is up-to-date as of December 15, 2025. For the most current information, please contact Wilson Yee, (408) 889-1808